Type 2 diabetes mellitus (T2DM) is a common disease associated with numerous complications. Obesity is the leading cause of the increased incidence of type 2 diabetes mellitus in both developed and developing countries. Obesity and overweight have in the last decade become a global problem - according to the World Health Organization (WHO). There are many risk factors for type 2 diabetes.
It is an astonishing fact that the number of people having Diabetes Mellitus (DM) is increasing day by day. Asians have higher incidence of Diabetes, due to genetic reason. Life style changes and food habits contribute to this increase. Diabetes affects all organs in the body like eye, brain, heart, kidney & limb vessels. These lead to early death.
International Diabetic federation has approved bariatric surgery as preferred and effective treatment of diabetes; benefits of surgery being long lasting remission of diabetes; control of other associated illnesses and cost effectiveness.
NEJM (New England Journal of Medicine) rates metabolic surgery to cure Diabetes as the most important innovation of 2012.
Type 2 Diabetes is the result of
It is now clear the intestinal hormone (GLP1) levels can regulate the insulin production in pancreas. Hence by increasing GLP1 level in the gut, diabetes can be controlled. GLP1 is produced in large quantities by terminal portion of small intestine. Partially digested food reaching this region increases the production of this hormone. There are other neurohormonal gut mechanisms as well, working in favour to control of diabetes.
By keyhole surgery the stomach size is brought down hence excess food intake will be reduced and gastric emptying is accelerated. Last portion of small intestine is brought towards the stomach that helps in bringing partially digested food into the small intestine rapidly, thus increasing GLP1 level and there by increasing insulin levels. Obese diabetics require modified sleevegastrectomy alone while non obese diabetics require sleeve gastrectomy and ileal interposition. The weight reduction and associated fat loss will also increase insulin activity. These surgeries are found to increase insulin performance and give long standing resolution of diabetes.
These procedures are helpful in patients with Type 2 diabetes, in whom pancreas is capable of producing good level of insulin. These are having much better result in those with more than ideal weight and in those with diabetes of shorter duration (few years) than in those who have already damaged their end organs like kidney, eye, heart, etc. So it is better to undergo this procedure before pancreas fails significantly and before end organs damage starts. It is highly appreciable for a diabetic patient to know that cure is possible. In Type I diabetes (where pancreas is not functioning at all or has antibodies against insulin) these surgeries are not helpful.
85% to 90% of diabetic patients treated by these surgeries are cured of diabetes. Other 10 to 15% also could reduce their medications significantly. In addition to diabetic control the other benefits are loss of excess weight and control of cholesterol, sleep apnoea, joint pains, cardiac disease, hypertension, kidney disorders, eye problems etc. It definitely improves quality of life and reduces cancer risk, infertility & mortality (early death).
All these procedure are done under general anaesthesia and patient will be observed for 4 days in hospital. These are done by laparoscopic and minimally invasive methods using equipments like staplers & harmonic scalpel. Hence, patients will be highly comfortable and can resume normal activity in a few days time.